Centre for Bioinformatics  

In view of rapidly growing importance of Information Technology in Biotechnology teaching and research, related software, data management, communication etc., Centre for Bioinformatics (a sub-DIC under BTIS programme) was sanctioned by Department of Biotechnology, Govt. of India in November, 1998. Over the last nine years, this centre has acquired many databases and softwares and has round the clock Internet connectivity.  

The Centre has 3 servers, 25 PCs, 1 scanner, 9 printers, 1 LCD projector, 2 IBM Thinkpads, 2 Web Camera, 1 Digital Camera, 4 CD Writers, 1 Konika 1212 Photocopier, several software and databases. All computers are connected   to Internet through 512 KBPS lease line from BSNL under campus networking.

  • It is extensively used by PG students in Biotechnology, Bioscience and Bioinformatics, Ph.D. students and the teaching faculty in the following ways:

  •    Searching literature/databases of their own research interest.

  •    E-mail facility                               

  •    Computational work.    

  • The services of the Centre for Bioinformatics include analysis of   biological data, bibliographic references to published literature in Science and Technology.
     

Coordinator, Bioinformatics Centre: Prof. Vinay Sharma, Dean, Faculty of Science

The staff members working in the centre are:


S.No Name of the Staff

Designation

Educational Qualification/ Specialization
1.

Ms. Saroj Yadav

Information Officer

M.Sc. Bioinformatics
2.

Mrs. Kiran Shanti

Technical Assistant

P.G.D.C.A.
3.

Mr. S. R. Choudhary

Computer Operator

A.D.C.A., P.G.D.C.T.A. I.T.

4.

Mr. K. M. Jangid

Computer Operator

‘A’ Level , C++

5.

Mr. Amit Goyal

Data Entry Operator  

‘O’ Level, MCSE, CCNA

 Major research activities in Biotechnology

The Ph.D. students carry out research in various disciplines of Biotechnology, Bioscience and Bioinformatics.  There are sponsored research projects with teaching faculty of the department. Some of the Agricultural Biotechnology related research topics are: Phytoalexins; Immobilization of enzymes; Fluoride toxicity; Reclamation of desert soils using plants; Tissue culture of arid zone species etc.    

A  research collaboration in the area of Crop Biotechnology (on stress adaptation of plants of local region) is being worked out between Prof. Vinay Sharma’s laboratory at this Department and Prof. U. Luettge’s laboratory at Institute of Botany, Technical University, Darmstadt.  


A research collaboration of a few faculty members with laboratories in Germany and USA. Prof. Vinay Sharma has been a Visiting Professor at the Department of Molecular Biology and Microbiology, University of Florida, USA (January to May, 2006).  


Dr. Bhumi Nath Tripathi, Senior Lecturer was awarded the prestigious DBT Young Scientist Overseas Associateship and visited the laboratory of Prof. Karl-Josef Dietz, University of Bielefeld, Germany (July to November, 2006)  


Dr. Bhumi Nath Tripathi, Senior Lecturer was a Visiting Scientist at the Research Institute of Bioresources, Okayama University, Japan (October 07-March 08).       

  • Some of the important databases in Biological Sciences that are currently available are: Medline Standard, Agris, Agricola, Chrome Circle Application, Biotechnology Abstracts and Indian Forester Information System.
     

  • To cater to the regional and national needs, the Centre has also developed database on "Biotechnological Industries of Rajasthan", “SSR Database of Citrus sinensis,”, “Database for Simple Sequence Repeats of Takifugu rubripus” and “Database of  Diterpene Synthase Gene”. The work on the other databases "Flora of Indian Desert", and “Database of Plant Host-Pathogen interaction” is in progress.


S.No Name of Database        Broad Subject Area Broad Functional Area Developed/ Acquired Completion Status
1.

Biotechnological Industries of Rajasthan

Bioinformatics /Biotechnology

Biotechnology Developed Completed
2.

SSR Database of Citrus sinensis

Bioinformatics

Bioinformatics Developed Completed  
3.

Database for Simple Sequence Repeats of Takifugu rubripus

Bioinformatics

Bioinformatics Developed Completed
4.

Database of Diterpene Synthase Gene

Bioinformatics

Bioinformatics Developed Completed
5.

Database of Flora of Indian Desert  

Bioinformatics/ Plant Science

Biodiversity Developed In Progress
6.

Database of Plant Host-Pathogen Interaction

Bioinformatics/ Plant Science

Biodiversity Developed In Progre


Manpower Training:

To generate trained manpower in Bioinformatics, National Workshops with participation of University level teaching faculty/ Scientists are regularly organized by the Centre. The following workshops were organized in past:  

      Table:
      The workshops organized by the Centre for Bioinformatics, Dept. of Bioscience & Biotechnology during the last few
      years:
  
  

Year Name of the Seminar/ symposia Duration Participation details
2001

“Application of Internet in Advanced Teaching and Research in Biological Sciences”

3 days

41 Participants of Reader / Lecturer / Research Scientists and Research Scholars rank from Univ. and College from various States
2002

“Application of Information Technology in Biotechnology based research”

2 days 39 Participants of Prof./ Reader/ Lecturer / Research Scientists and Research Scholars rank from Univ. and Colleges from various States
2004

“Trends in Bioinformatics”

2 days 51 Participants of  Reader/ Lecturer / Research Scientists and Research Scholars rank from Univ. and Colleges from various States
2005

“Bioinformatics Basics- Application in Biological Sciences”

2 days 63 Participants of Reader/ Lecturer / Research Scientists and Research Scholars rank from Univ. and Colleges from various States
2007

“Biological Databases and Data  Mining” 

3 days 66 Participants of Reader/ Lecturer / Research Scientists and Research Scholars rank from Univ. and Colleges from various States
2008

"Computational Approaches in Biological Data Mining"

3 days Proposed (Dec. 6-8 ,2008)
    
 Bioinformatics Research Papers Published, in peer Reviewed journal by our centre.
  1. Shanker A., Bhargava A., Bajpai R., Singh S., Srivastava S. and Sharma V. (2007). Bioinformatically mined simple sequence repeats in unigene of  Citrus sinensis. Sci. Horti. 113: 353-361.
  2. Shanker A., Singh A. and Sharma V. (2007). In silico mining in expressed sequences of Neurospora crassa for identification and abundance of microsatellites. Microbiological Research 162: 250-256.
  3. Singh, A., Mishra, S., Raghav, D., Shanker, A. and Sharma, V. 2008. In silico method for the identification of Mycobacterial sp. Potential drug targets. ICCES, 174: 1-5.
  4. Grover A. and Sharma P.C. (2007). Mocrosatellite motifs with moderate GC content are clustered around genes on Arabidopsis thaliana chromosome 2. In Silico Biol. 7: 0021.
  5. Grover A., Aishwarya V., and Sharma P.C. (2007). Baised distribution of microsatellite motifs in the rice genome. Mol Gen Genomics 277:469-480. 
  6. Aishwarya V., Grover A. and Sharma P.C. (2007). EuMicroSatdb: A database for in Silico mining of Microsatellites. BMC Genomics 7: 201-213.
  7. Shanker A., Tripathi D., Khandelwal G., Sharma G., Agrawal S., Singh A. and Sharma V. (2006). Data mining and database development for simple sequence repeats of Takifugu rubripes (Japanese Pufferfish).Biochem. Cell. Arch. 6: 1-12.
  8. Shanker A., Kumar A., Sangwan C., Chowdhary N., Gupta S., Sonica and Sharma V. (2007). Orthologous and Essential Genes Identification in Cryptococcus neoformans and Neurospora crassa in joint Indo Korean Symposium On Biochemical Engineering & Biotechnology , 22nd -24th February, New Delhi, India.
  9. Singh A., Shanker A., Mishra S., Srivastava S., Singh S., Vijay T., Gupta V., Kulshrestha R., Sharma V. Essential Genes Finding and Potential Drug Targets Identification of M. tuberculosis in HIV/AIDS and TB: Past, Present and Future: 2006 at AIIMS Golden Jubilee Celebrations, January 13th to 15th 2006.
  •   Book Published:

  1. Sharma V., Munjal A. and Shanker A. (2008). Textbook of Bioinformatics.  Rastogi Publications, Meerut.


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